Pituitary
inflammatory lesions are uncommon: a granulomatous inflammatory reaction can be
caused by systemic tuberculosis, syphilis or fungal infections, being usually an
incidental autopsy finding. They come to the pathologist more frequently when
they are at an advanced stage, producing a mass effect and/or hypothalamic.
However, the most enigmatic form of granulomatous hypophysitis is idiopathic. Exceptional
is the association of this inflammatory lesion with adenomatous neoplastic one.
The aim of our report was to make assumptions on the pathogenesis of this
unlikely association.
Case
Report: We report the case of a 50-year-old male with a history of frontal
headache lasted for years. In the last three years he had noticed an
unexplained weight gain, decreased libido and sporadic visual defects. For this
reason, he went to an eye doctor who suggested to make a magnetic resonance
(MRI) of the brain which revealed an intrasellar tumor with slight suprasellarextension, displaying areas of hemorrhage and necrosis, most likely a pituitary
macroadenoma. A computerized examination of the visual field highlighted a
temporal hemianopsia of the left eye. Read more>>>>>>>>>>>>>
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