Secretory carcinoma is a rare
low-grade breast carcinoma, characterized by the presence of large amounts of
intracellular and extracellular secretory material and composed of cells with granular eosinophilic or amphophilic cytoplasm. This tumor frequently occurs in
either children or adolescents.
Though it is considered rare in adults, it is
potentially more aggressive than in children. Originally this tumor was
described in children, but it is now known to occur in adults of both sexes
including a substantial number of post-menopausal women. We present the case of
a 66-years-old woman with juvenile secretory carcinoma of the breast treated by
mastectomy and axillary node dissection.
Case
Report: A 66-year-old female patient presented with a subareolar mass of the
right breast since 5 years. The mass suddenly increased in size with no
evidence of palpable axillary lymph nodes. Serum tumor markers and other
routine blood test were normal. The liver ultrasonography and chest X-ray were
negative for metastases. A radical mastectomy with axillary node dissection was
decided and performed. Grossly, the mass was circumscribed, measured 50 × 35 mm
and had white glistening cut section. Microscopic examination revealed the
classical features of secretory carcinoma with microcystic, papillary and solid
patterns with abundant intra and extracellular PAS-positive secretory material. Read more>>>>>>>>>>>>>>>
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