Bovine
leukemia is a disease reported by Leisering in 1871, associated with bovine
cattle. Leisering identified in some of the animals with this disease, the
development of splenomegaly and persistent lymphocytosis while most of them
remain asymptomatic. Furthermore, it was noticed that the presence of this
disease could lead to important economic losses to dairy and meat herds, as
well as dual-purpose bovine herds, due to the fact that milk production and
weight development are affected.
In addition, infected animals become
susceptible to acquiring secondary infections what decreases their health
conditions and thus their expected production yield. Later on, in 1969, Miller
and co-workers identified the associated pathogen to the disease, which is
known nowadays as the Bovine Leukemia Virus (BLV). Afterward, it was described
as an enveloped retrovirus, with a size between 80-125 nm. It is classified as
a deltaretrovirus, belonging to Retroviridae family, Orthoretrovirinae
subfamily. In this group, are also classified HTLVs, viruses related with neoplastic
processes in humans. Read more>>>>>>>>>>

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